Plasmaphoresis

As we age, our blood accumulates harmful proteins and inflammatory molecules that can negatively impact nearly every system in the body. It’s a subtle but powerful force behind cognitive decline, chronic inflammation, and cellular dysfunction. At Dignity Medical in El Dorado Hills, we offer therapeutic plasmapheresis—an advanced, science-backed approach to detoxifying the bloodstream and restoring optimal internal balance.

What Is Plasmapheresis?

Plasmapheresis, also known as Therapeutic Plasma Exchange (TPE), is a medical procedure that filters the blood to remove damaged or toxic components in the plasma. Your blood is made up of two primary parts: red and white blood cells (along with platelets), and plasma—the liquid portion that carries nutrients, hormones, proteins, and waste products.

Over time, this plasma can become “polluted” with pro-inflammatory cytokines, autoantibodies, oxidized proteins, and other cellular debris. These unwanted molecules can interfere with healthy cell function, contribute to neurodegenerative diseases, and accelerate the aging process. Plasmapheresis works by removing the patient’s plasma, separating out these harmful agents, and replacing it with clean, healthy plasma substitutes or donor plasma—effectively giving your circulatory system a fresh start.

Why It Matters for Longevity

Your blood is the medium that nourishes every cell in your body. When your plasma is clean and well-balanced, your cells thrive. When it’s saturated with inflammatory and oxidized proteins, cellular aging speeds up. Think of it like the oil in your car—when it’s fresh, everything runs smoothly. But when it’s thick with debris, it begins to damage the engine over time.

This concept has become a central theme in cutting-edge longevity research. Studies show that removing aged, damaged plasma and replenishing it with clean fluid may reduce markers of inflammation, improve brain function, and rejuvenate key systems like the immune and cardiovascular networks.

At Dignity Medical, we see plasmapheresis not as a luxury, but as a powerful medical tool for those who are serious about aging better, preventing disease, and restoring clarity and vitality at the cellular level.

Who Can Benefit from Therapeutic Plasma Exchange?

Plasmapheresis has long been used in hospital settings for autoimmune disorders and neurological conditions. However, more recently, it has gained traction in the realm of preventive and regenerative medicine, particularly for those seeking proactive longevity care.

Individuals who may benefit include:

• Those experiencing early signs of cognitive decline, brain fog, or memory issues

• Patients with chronic inflammation or autoimmune-related symptoms

• People recovering from long-term illness or toxic exposures

• Individuals pursuing a comprehensive longevity program and cellular rejuvenation

• High-performers or biohackers looking to optimize brain and body function

At Dignity Medical, we perform in-depth assessments before recommending plasmapheresis. We want to ensure the therapy is appropriate, safe, and complementary to your unique health status and long-term goals.

The Procedure: What to Expect

Plasmapheresis is a minimally invasive, outpatient procedure performed in a comfortable, clinical environment. During the treatment:

1. Blood is drawn from your body via a small catheter or IV.

2. It passes through a specialized machine that separates plasma from the blood cells.

3. The cellular portion of your blood is returned to your body, along with a sterile plasma substitute (such as albumin or donor plasma).

4. The process is repeated in cycles until a sufficient volume of plasma has been filtered.

Most sessions last about two to three hours, and many patients describe the experience as relaxing. You can listen to music, read, or simply rest during the procedure. Afterward, you’ll be monitored briefly before returning to normal daily activities.

Some patients report feeling energized or mentally clear following treatment. For others, the benefits build gradually over time. We will work with you to determine how often sessions should be scheduled, depending on your health profile and goals.

Safety and Expertise at Dignity Medical

Our clinical team is trained in advanced longevity protocols, and we take every precaution to ensure your safety and comfort. Prior to treatment, we conduct:

• Detailed lab testing

• Cardiovascular and metabolic assessments

• A thorough review of medical history

• Individualized risk evaluation

We also follow rigorous sterilization and transfusion standards to minimize any potential risks, and every procedure is overseen by experienced medical professionals.

A Key Player in Our Longevity Protocol

Plasmapheresis is just one piece of the puzzle. At Dignity Medical, we view it as a complement to your broader wellness strategy. Whether you’re also pursuing hormone optimization, IV infusions, micronutrient support, or advanced diagnostic testing, our goal is to create a synergistic treatment plan that works with your biology and supports long-term cellular health.

Our patients are often high achievers—entrepreneurs, executives, athletes, parents, and professionals—who want more than just to “feel okay.” They want to feel sharp, capable, and energized as they age. Plasmapheresis is one of the most powerful tools available for those ready to take longevity seriously.